How to make mercaptopropionic acid MPA?

Publish Time: 2023-08-26     Origin: Site

How to make mercaptopropionic acid MPA?

There are three main methods for preparing mercaptopropionic acid: 

  1. Acrylonitrile is synthesized by acidolysis after the addition reaction with sodium thiohydride;

   2. Acrylic acid is obtained by addition reaction with hydrogen sulfide, or by hydrolysis after addition of acrylic acid with sodium thiosulfate; 

   3.3- Chloropropionic acid is obtained by nucleophilic substitution with sodium trithiocarbonate and acid hydrolysis.

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